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Pioneering PCR for HIV Detection
About Dr. Jose A. Giron, MD, FACP
A Pioneer in Infectious Disease Medicine
Dr. Jose A. Giron at Sunshine Specialty Healthcare provides advanced infectious disease treatment for patients across Orlando and Central Florida, a board-certified Infectious Disease Specialist with more than 45+ years of clinical experience diagnosing, treating, and managing complex infectious diseases. He is widely respected for his medical expertise, research contributions, and compassionate, patient-centered approach to care.
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Earned his medical degree from Harvard Medical School and completed his Internal Medicine residency and Infectious Disease fellowship at Mount Sinai Hospital, New York.
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Has extensive experience treating a wide range of infections, from common communicable illnesses to complex and life-threatening conditions affecting immunocompromised patients.
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Participated in numerous clinical research trials and authored multiple peer-reviewed publications in the field of infectious diseases.
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Holds particular expertise in HIV care, Hepatitis B and C management, and complex infectious disease treatment.
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His research and clinical work are widely cited and recognized within the medical community.
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In addition to patient care, he is a dedicated medical educator who has trained medical students, residents, and fellows.
"Infectious diseases are often complex, but your care shouldn't be. My goal is to combine Ivy League clinical precision with a deeply personal approach, ensuring every patient — regardless of their diagnosis — receives a clear path to recovery and long-term wellness."
~ Dr. Jose A. Giron, MD, FACP
A Pioneer in Medical Research & Global Breakthroughs
Dr. Jose A. Giron’s contributions to medical science have fundamentally changed how infectious diseases are diagnosed and treated in the United States:
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Pioneering PCR Implementation: Dr. Jose A. Giron was an early pioneer in the clinical use of PCR (Polymerase Chain Reaction) for HIV-DNA Detection for early-stage diagnosis and viral load monitoring.
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First-in-Medicine Discovery (Lyme & Babesia): He published the first-ever clinical description of a patient co-infected with Lyme Disease and Babesia, a landmark finding for the diagnosis of complex, treatment-resistant tick-borne illnesses.
A Personal Path to Compassionate Care
Dr. Jose A. Giron’s commitment to serving the diverse communities of Central Florida is rooted in his own history. As a child, he was part of Operation Pedro Pan—the historic exodus of over 14,000 unaccompanied Cuban children to the United States.
Having navigated the challenges of being a young refugee and immigrant himself, Dr. Jose A. Giron understands that healthcare is about more than just a diagnosis—it’s about dignity, safety, and a sense of belonging.
Clinical Philosophy: Integrated & Evidence-Based Care
Dr. Jose A. Giron’s approach at Sunshine Specialty Health Care is rooted in the belief that treating an infection requires looking at the whole person. He combines Ivy League training with a "humanized" communication style to ensure patients feel heard and empowered.
A key part of his practice is managing Metabolic and Endocrine health alongside infectious diseases, recognizing that conditions like blood sugar or thyroid function directly impact the immune system. He works closely with our primary care doctor at Sunshine Specialty Health Care OR at the clinic of your choice to address your metabolic and endocrine health issues
Education & Clinical Expertise
Dr. Jose A. Giron’s authority is anchored by elite education and rigorous clinical training at some of the world's leading medical institutions.
Medical School/Academic Excellence
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Harvard Medical School – Harvard University, Boston, MA
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Medical Education & Advanced Clinical Training
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Post-Graduate Clinical Training
Dr. Jose A. Giron completed a decade of specialized training at The Mount Sinai Hospital in New York, a global leader in complex medical care:
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Fellowship (Infectious Disease) * Icahn School of Medicine at Mount Sinai, 1978–1980
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Residency (Internal Medicine) * Icahn School of Medicine at Mount Sinai, 1976–1978
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Internship (Transitional Year) * Icahn School of Medicine at Mount Sinai, 1975–1976
Professional Certifications & Leadership
To ensure the highest standards of care, Dr. Jose A. Giron is dual-certified and holds prestigious fellowships:
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Board Certified in Infectious Disease – The American Board of Internal Medicine
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Board Certified in Internal Medicine – The American Board of Internal Medicine
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Fellow of the American College of Physicians (FACP)
Active Member, Infectious Diseases Society of America (IDSA)
Research Contributions & Clinical Leadership
Dr. Jose A. Giron has a lifelong commitment to advancing the field of infectious disease through clinical research and peer-reviewed presentations. His work has contributed significantly to the medical community’s understanding of viral detection and the management of complex pathogens.
Selected Medical Publications & Presentations
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PCR Detection of Integrated HIV-DNA in Peripheral Blood Lymphocytes
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Presented At: American Society for Microbiology Meeting
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Date: May 1991
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Focus: Pioneering research into Polymerase Chain Reaction (PCR) technology for early and accurate HIV detection.
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Aerosolized Pentamidine vs. Trimethoprim: Comparative Analysis
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Presented At: Sixth International AIDS Conference
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Date: June 1990
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Focus: Clinical study on the effectiveness of treatments for opportunistic lung infections in immunocompromised patients.
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An Outbreak of Serratia Marcescens in the NICU
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Source: Peer-Reviewed Medical Literature
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Focus: A critical analysis of hospital-acquired bacterial outbreaks and strategies for containment and prevention in high-risk clinical settings.
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Read More of Dr. Jose A. Giron's Medical Publications
Professional Affiliations & Hospital Privileges
Dr. Jose A. Giron’s medical authority is recognized by the nation's leading healthcare institutions, ensuring that patient care is backed by the highest standards of clinical excellence.
Elite Professional Fellowships & Memberships
These designations are awarded only to physicians who demonstrate a lifetime of dedication to medical excellence and peer-reviewed research:
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Fellow of the American College of Physicians (FACP): A mark of distinction representing the highest level of expertise and integrity in Internal Medicine.
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Infectious Diseases Society of America (IDSA): Active membership in the global leader for infectious disease research and clinical guidelines.
Hospital Affiliations & Local Care Coordination
To provide the highest level of integrated medical care, Dr. Jose A. Giron maintains active medical staff privileges at Central Florida’s leading healthcare institutions. This ensures that if a patient requires hospitalization or advanced surgical intervention, their care plan remains unified and transition-free.
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Active Medical Staff Privileges: Dr. Giron is an integrated part of the Orlando healthcare infrastructure, maintaining active privileges at the region's premier medical centers:
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AdventHealth Orlando (Formerly Florida Hospital) is recognized as one of the largest and most respected tertiary facilities in the region.
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Orlando Health (ORMC): Orlando Regional Medical Center is a flagship institution and home to the area’s only Level One Trauma Center.
Infectious Disease Conditions & Specialized Services Treated by Dr. Jose A. Giron at SSHC
Under the expert leadership of Dr. Jose A. Giron, Sunshine Specialty Healthcare in Orlando provides precise, evidence-based treatment for a wide range of acute, chronic, and treatment-resistant infections.
Blood-Borne Viruses & Chronic Management
Dr. Giron provides expert, long-term management for complex viral pathogens, focusing on viral load suppression and immune health.
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HIV/AIDS Care: Comprehensive management including 4th-Generation Antigen/Antibody assays with 15-20 minute in-office results.FREE TESTING FOR ALL PATIENTS.
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Hepatitis B & C: Specialized evaluation and antiviral therapy protocols.
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Emergency Prevention: Immediate access to PEP (must be started within 72 hours of exposure) and routine PrEP management.
Specialized & Treatment-Resistant Infections
We specialize in managing "difficult-to-treat" cases that require advanced antimicrobial stewardship.
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Drug-Resistant Pathogens: Targeted protocols for MRSA and other Multidrug-Resistant Organisms (MDROs).
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Bone, Joint & Post-Surgical Infections: Expert care for Osteomyelitis, Septic Arthritis, and infections following major surgery.
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Fever of Unknown Origin (FUO): Detailed clinical investigation to uncover and treat the source of persistent, undiagnosed fevers.
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Serious Bacterial & Fungal Care: Management of Endocarditis (heart lining infection), Tuberculosis (TB), and complex fungal infections like Aspergillosis.
Tropical, Tick-Borne & Viral Illnesses
Dr. Giron is a recognized expert in identifying rare and emerging pathogens.
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Tick-Borne Illness: Specialized diagnosis and treatment for Lyme Disease and parasitic infections.
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Communicable Viruses: Advanced treatment for Influenza, RSV, Shingles, and Long-COVID recovery.
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Sexually Transmitted Infections (STIs): Discrete, confidential testing and treatment for Syphilis, Chlamydia, Gonorrhea, Herpes, and HPV.
Advanced Outpatient Services
To provide a sophisticated alternative to hospital admission, our clinic offers high-level medical interventions in a comfortable office setting:
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In-Office IV Infusion Therapy: Specialized IV antibiotic and antifungal treatments.
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Rapid Diagnostics: For HIV/Hepatitis we provide On-site laboratory interpretation for faster clinical decision-making.Rest of the lab draws will be sent to Quest or Labcorp for additional testing.
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Targeted Antimicrobial Therapy: Precision-guided antibiotic, antiviral, and antifungal treatments tailored specifically to your unique health profile and diagnosis.
At Sunshine Specialty Health Care, your health is our priority.
Why Dr. Jose A. Giron is a Leading Infectious Disease Specialist in Orlando
Patients across Central Florida trust Dr. Jose A. Giron for his rare combination of Ivy League precision and a deeply personal, patient-centered approach to medicine.
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Elite Ivy League Training: As one of the few Harvard-trained Infectious Disease specialists in the Orlando region, Dr. Giron brings a world-class level of clinical expertise to our local community. His background in pioneering viral research ensures that even the most complex cases are handled with the highest level of medical authority.
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Multilingual Support & Accessibility: To ensure every patient feels heard and understood, Dr. Giron provides high-level medical consultations in English, Spanish, French, and Italian. This eliminates communication barriers and ensures that complex medical details are explained clearly in the patient’s native language.
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Advanced Outpatient Facilities: We provide a sophisticated alternative to hospital-based care. Patients have direct access to in-office IV infusions and rapid, 4th-generation diagnostics, allowing for intensive treatment without the high cost or stress of a hospital admission.
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Compassionate, "Humanized" Listening: Dr. Giron has built a 45-year reputation for taking the time to listen. He is known for explaining complex infectious disease diagnoses in simple, human terms, ensuring that patients leave their appointments feeling empowered and informed rather than overwhelmed.
Specialized Clinical Services & Diagnostic Excellence At Sunshine Specialty Healthcare
At Sunshine Specialty Health Care, Dr. Jose A. Giron provides a full spectrum of advanced services, from routine diagnostic consultations to the management of complex, long-term medical conditions.
Diagnostic & Consultative Precision
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Comprehensive Consultations: In-depth evaluations for acute symptoms, travel-related illnesses, and complex Fevers of Unknown Origin (FUO).
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Advanced Evaluation: Expert interpretation of intricate laboratory results, cultures, and molecular testing to identify specific pathogens quickly.
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Coordinated Care: We offer seamless collaboration with local Orlando hospitals and specialty providers to ensure your treatment plan is unified and effective.
Chronic Disease & Long-Term Management
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HIV Care and Management – Evidence-based, long-term treatment plans focused on viral suppression and overall wellness.
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Hepatitis B & C Evaluation – Specialized treatment protocols to manage viral hepatitis and protect long-term liver health.
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Post-COVID & Long-COVID Care – Clinical support and symptom management for individuals experiencing persistent health issues following a viral infection.
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Management of Rare & Complex Infections – Expert care for treatment-resistant pathogens and rare medical conditions requiring high-level specialized knowledge.
Preparing for Your First Consultation
A specialized infectious disease evaluation is more comprehensive than a standard check-up.
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Gather Your Medical Timeline: Please bring current medications, previous lab results, vaccination records, and a 24-month travel history.
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What to Expect: Your 30–45 minute visit includes a Comprehensive Clinical Review, physical exam, and potential Precision Diagnostics.
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Arriving at the Clinic: We are located at 1727 Orlando Central Pkwy, Orlando, FL 32809. Please bring a government ID and insurance card.
Schedule a Consultation with Dr. Jose A. Giron
Dr. Jose A. Giron is currently welcoming new patients at Sunshine Specialty Healthcare in the Orlando location. Whether you are seeking a second opinion, specialized HIV care, or treatment for a recurring infection, expert help is available.
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Same-day appointments available based on insurance
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Self-pay patients welcome
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Telehealth options available
Visit Our Orlando Clinic
We are conveniently located in the Orlando medical district to serve patients across Central Florida:
Address: 1727 Orlando Central Pkwy, Orlando, FL 32809
Office Hours: [Monday – Friday: 8:00 AM – 5:00 PM]
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Yes. Dr. Jose A. Giron is currently accepting new patients for comprehensive HIV management, as well as PrEP (Pre-Exposure Prophylaxis) and PEP (Post-Exposure Prophylaxis). Our clinic also provides expert guidance for Florida assistance programs like ADAP and Ryan White to ensure your care is accessible and affordable.
We prioritize urgent medical needs, such as PEP (Post-Exposure Prophylaxis)—which must be started within 72 hours of exposure—and acute bacterial infections. Please call our Orlando office as early as possible to check for same-day availability.
Many serious infections require intravenous (IV) antibiotics or antifungals. Instead of a costly hospital stay, Dr. Jose A. Giron provides this high-level treatment in our comfortable Orlando clinic. This allows you to receive hospital-grade antimicrobial therapy while returning to the comfort of your home the same day.
Yes. Investigating persistent, undiagnosed fevers is one of Dr. Jose A. Giron’s primary specialties. Using advanced diagnostic evaluation and his 45+ years of clinical experience, he performs deep-dive medical investigations to uncover the root cause of complex symptoms.
To ensure every patient feels comfortable discussing sensitive health matters, Dr. Jose A. Giron provides high-level medical consultations in English, Spanish, French, and Italian.
Absolutely. Dr. Jose A. Giron has extensive experience managing Multidrug-Resistant Organisms (MDROs), including MRSA. He uses targeted antimicrobial therapy and precision-guided treatment plans to manage infections that have not responded to standard antibiotics.
Yes. We provide specialized evaluation and long-term treatment protocols for both Hepatitis B and Hepatitis C. Our goal is to manage viral loads effectively and protect your long-term liver health through evidence-based care.
Our clinic utilizes 4th-Generation HIV Antigen/Antibody assays, which allow us to provide rapid, highly accurate results in-office, typically within 15 to 20 minutes.
Yes. Dr. Jose A. Giron maintains active medical staff privileges at AdventHealth Orlando and Orlando Health (ORMC). If your condition requires hospitalization or specialized surgery, he coordinates directly with your hospital care team to ensure a unified treatment plan.
Our clinic is located at 1727 Orlando Central Pkwy, Orlando, FL 32809. While initial consultations for complex infections are best handled in person, we offer Telehealth options for established patient follow-ups, lab reviews, and routine chronic disease management.